wnicer RESEARCH INITIATIVES
consulting on & facilitating clinical trials
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WNICER implements research programs that shorten the time from discovery to patient benefit, including:
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Innovative clinical trials
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See sample of clinical trails WNICER members are currently involved in
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Translational research
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See sample of publications by WNICER members in 2020
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Implementation strategies that impact clinical care and clinical practice
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Our clinical research expertise includes:
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Clinical trials consulting: feasibility, design, sample sizing, budgets
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Prospective trial design and execution
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Registry data analysis and research
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Population health
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Health outcomes
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Health economics/outcomes
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Electronic health records
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Big data
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AI
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Project management
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Global sites (see our network composition below)
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Partnerships with existing academic and clinical research organizations
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Recent and Ongoing Clinical Trials:
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Point-of-care pharmacogenomic testing for personalized antiplatelet therapy after PCI
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TAILOR PCI (Tailored Antiplatelet Therapy Following PCI) - multi-site, prospective, randomized trial testing the hypothesis that after PCI, using a genotyping strategy is superior to usual care in reducing a composite endpoint of major adverse cardiovascular events (MACE), i.e., non-fatal myocardial infarction, non-fatal stroke, severe recurrent ischemia, cardiovascular (CV) death, and stent thrombosis (primary endpoints) in CYP2C19 reduced function allele patients. The study enrolled 5,300 patients in 41 locations across four countries, and was published in the Journal of the American Medical Association (JAMA) on August 25, 2020.
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COVID-19 Trials
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TAILOR-COVID: genetic predictors of disease susceptibility and outcome
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ACT: randomized trial testing utility of hydroxchoroquine, azithromycin, and interferon in a 2x2 factorial design
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ATTACC: prophylactic versus therapeutic anticoagulation
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Get Involved:
There are many ways to participate in WNICER's clinical trials initiatives:
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Sponsor a trial
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Participate as a co-investigator
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Enroll your centre in an on-going trial
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Participate as a research subject on on-going trials
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Consult with the WNICER group to design a trial
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Send an email to WNICER to request more information.
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research grants
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One of WNICER's goals is to provide investigators with seed money towards pilot and feasibility studies that would generate preliminary data - with the end goal of being able to apply for national grants e.g. through the NIH.
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Get Involved:
We welcome sponsorship from industry and other organizations to fund these pilot study initiatives. Please send an email to WNICER for more information on how we can partner with us.
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